Signaling molecules of the Wnt family are ubiquitous in biology. From cnidaria to man, they are responsible for forming the basic shape of all organisms. Without Wnt, our body would not have a top or bottom, front or rear. ...
Cell & Microbiology
Nov 20, 2015
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Steroid hormones - hormones such as testosterone and estradiol - control various aspects of animal biology and are crucial for the proper functioning of the body. Produced and secreted by endocrine glands in the body, these ...
Cell & Microbiology
Nov 5, 2015
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(Phys.org)—Our bodies have highly regulated and integrated systems. One such system, the TGF-β cell signaling pathway, regulates many developmental processes. A malfunctioning TGF-β pathway is implicated in many diseases, ...
A public and scientific discussion is currently taking place focusing on the question whether substances at low concentrations may lead to health impairments in humans. For this reason, an increasing number of experimental ...
Biochemistry
Mar 16, 2015
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Think of a waterfall, and you might see why cell-signaling pathways are important to cancer research. As water cascades, it impacts everything downstream. And everything upstream affects the waterfall.
Cell & Microbiology
Mar 9, 2015
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A signaling pathway once thought to have little if any role during embryogenesis is a key player in the formation of the front-most portion of developing vertebrate embryos. Moreover, signals emanating from this region—referred ...
Cell & Microbiology
Jul 17, 2014
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Environmental influences such as ionizing radiation, intense heat or various chemical substances damage the DNA constantly. Only thanks to efficient repair systems can mutations – changes in the DNA – largely be prevented. ...
Cell & Microbiology
May 27, 2014
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In 2012, John B. Gurdon and Shinya Yamakana were awarded the Nobel Prize in medicine for discovering that adult cells can be reprogrammed into pluripotent ones (iPS); the cells obtained are capable of behaving in a similar ...
Cell & Microbiology
May 6, 2014
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For more than a century, scientists have suggested that the best way to settle the debate about how phenotypic plasticity—the way an organism changes in response to environment—may be connected to evolution would be to ...
Evolution
Mar 10, 2014
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The Wnt/β-catenin signaling pathway and microRNA 335 are instrumental in helping form differentiated progenitor cells from stem cells. These are organized in germ layers and are thus the origin of different tissue types, ...
Cell & Microbiology
Jan 23, 2014
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