New functions for 'junk' DNA?

DNA is the molecule that encodes the genetic instructions enabling a cell to produce the thousands of proteins it typically needs. The linear sequence of the A, T, C, and G bases in what is called coding DNA determines the ...

Transcription runs like clockwork

(Phys.org)—It's not just a few key genes and proteins that cycle on and off in humans in a 24-hour circadian pattern as the sun rises and falls. Thousands of genes in organs throughout the body show predictable daily fluctuations, ...

Mysterious m6A marks on RNA begin to yield their secrets

Chemical modifications that appear on some RNA transcripts may have evolved in part to help cells repair themselves after damage, and may also be a key to understanding important human diseases, according to new research ...

New tool for investigating RNA gone awry

RNA is a fundamental ingredient in all known forms of life—so when RNA goes awry, a lot can go wrong. RNA misregulation plays a critical role in the development of many disorders, such as mental disability, autism and cancer.

RNA origami enables applications in synthetic biology

Developing tools for precise control of biological processes has been one of the main pillars of the now mature field of synthetic biology. These scientific tools borrow principles from a multitude of research fields which, ...

Transcription elongation checkpoint discovered

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.

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