New evidence in embryonic stem cells shows that mammalian genes may all have a layer of control that acts essentially like the pause button on your DVR. The researchers say the results show that the pausing phenomenon, previously ...
Biotechnology
Apr 29, 2010
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0
A research team at Children's Hospital of Philadelphia (CHOP) has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA is pieced together (spliced) when ...
Molecular & Computational biology
Mar 25, 2019
0
204
A team of scientists, led by a biomedical engineer at The University of Texas at Austin, have demonstrated - for the first time - that mathematical models created from data obtained by DNA microarrays, can be used to correctly ...
Biotechnology
Oct 14, 2009
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Once upon a time, scientists thought RNA polymerase—the molecule that kicks off protein synthesis by transcribing DNA into RNA—worked like a wind-up toy: Set it down at a start site in our DNA and it would whir steadily ...
Cell & Microbiology
Apr 24, 2015
0
32
When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding ...
Cell & Microbiology
Oct 25, 2010
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Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription.
Molecular & Computational biology
May 2, 2019
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126
Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into ...
Cell & Microbiology
Feb 22, 2018
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101
Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases.
Biotechnology
Dec 21, 2020
0
41
The totality of RNA molecules in an organism at any one time is the product of a delicate dance. Genes must be "turned on," or expressed, in order to turn DNA into RNA and then that RNA into proteins that accomplish an organism's ...
Cell & Microbiology
Oct 13, 2016
0
155
University of Toronto researchers have created a first-in-class functional catalog of proteins that activate gene expression, with implications for tailored therapy for cancer and other diseases that occur when wrong genes ...
Molecular & Computational biology
Feb 9, 2022
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