Tweaking the transcriptome to tackle stress
Single-celled plankton known as dinoflagellates are shown to cope with stress using an unexpected strategy of editing their RNA rather than changing gene expression levels.
Single-celled plankton known as dinoflagellates are shown to cope with stress using an unexpected strategy of editing their RNA rather than changing gene expression levels.
Biotechnology
Apr 17, 2017
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Octopuses, squid, and cuttlefish often do not follow the genetic instructions in their DNA to the letter. Instead, they use enzymes to pluck out specific adenosine RNA bases (some of As, out of the As, Ts, Gs, and Us of RNA) ...
Biotechnology
Apr 6, 2017
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Sequencing messenger RNA molecules from individual cells offers a glimpse into the lives of those cells, revealing what they're doing at a particular time. However, the equipment required to do this kind of analysis is cumbersome ...
Biotechnology
Feb 13, 2017
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Yukiko Shimada, Fabio Mohn, and Marc Bühler at the FMI elucidated an important mechanistic detail of small RNA mediated chromatin silencing. They showed in fission yeast that the small RNA in the RNA induced silencing complex ...
Cell & Microbiology
Dec 22, 2016
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The totality of RNA molecules in an organism at any one time is the product of a delicate dance. Genes must be "turned on," or expressed, in order to turn DNA into RNA and then that RNA into proteins that accomplish an organism's ...
Cell & Microbiology
Oct 13, 2016
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A tiny therapeutic delivery system that can control the body's ability to manufacture proteins has been developed by Saudi Arabia's King Abdullah University of Science and Technology (KAUST) researchers.
Bio & Medicine
Sep 23, 2016
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Researchers propose "Oritatami" as a mathematical model of the cotranscriptional folding of RNA in order to widen applications of RNA origami—one of the most significant experimental breakthroughs in molecular self-assembly.
Cell & Microbiology
Jul 6, 2016
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Rutgers University scientists have discovered the three-dimensional structure of a gene-specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn ...
Cell & Microbiology
Jun 9, 2016
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Gene transcription is the process by which DNA is copied and synthesized as messenger RNA (mRNA)—which delivers its genetic blueprints to the cell's protein-making machinery.
Cell & Microbiology
May 26, 2016
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A key biochemical enables bacteria to repair otherwise fatal damage to their DNA, including that caused by antibiotics. That is the finding of a study led by researchers at NYU Langone Medical Center and published May 20 ...
Cell & Microbiology
May 19, 2016
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