Preventing the spread of repression

Scientists at the Friedrich Miescher Institute for Biomedical Research have identified a novel and unexpected regulatory activity of RNA at the edge of inactive chromosomal regions. In their publication in Nature Structural ...

'Rhythm' of protein folding encoded in RNA, biologists find

(Phys.org)—Multiple RNA sequences can code for the same amino acid, but differences in their respective "optimality" slow or accelerate protein translation. Stanford biologists find optimal and non-optimal codons are consistently ...

Raising the blockade

At crucial points in the metabolism of all organisms, a protein with the unwieldy name of Translation Elongation Factor P (EF-P, for short) takes center stage. What it actually does during protein synthesis has only now been ...

RNA folding: A little cooperation goes a long way

(Phys.org)—The nucleic acid RNA is an essential part of the critical process by which the cells in our bodies manufacture proteins. But noncoding RNAs also exist whose sequences, while not converted into proteins, play ...

The controlled cell

(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the cell. Supported ...

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