Short RNA molecules mapped in single cell

Researchers at Karolinska Institutet have measured the absolute numbers of short, non-coding, RNA sequences in individual embryonic stem cells. The new method could improve the understanding of how our genes are regulated ...

Identifying molecular guardian of cell's RNA

When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding ...

No knots in known RNA structures

It had never been verified before: unlike other biopolymers, RNA, the long strand that is 'cousin' to DNA, tends not to form knots. The observation has been published in the journal PNAS by a research team of the International ...

Male beetles neglect their genomes when competing for females

Male beetles face a trade-off between competing with other males for mating opportunities and repairing damage to their sperm DNA, according to a study published April 4 in the open access journal PLOS Biology by Mareike ...

Detecting E. coli strains using molecular electronics

Finding a fast and inexpensive way to detect specific strains of bacteria and viruses is critical to food safety, water quality, environmental protection and human health. However, current methods for detecting illness-causing ...

Efficient mRNA delivery by branched lipids

Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...

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