Preventing the spread of repression

Scientists at the Friedrich Miescher Institute for Biomedical Research have identified a novel and unexpected regulatory activity of RNA at the edge of inactive chromosomal regions. In their publication in Nature Structural ...

Broad-scale genome tinkering with help of an RNA guide

Duke researchers have devised a way to quickly and easily target and tinker with any gene in the human genome. The new tool, which builds on an RNA-guided enzyme they borrowed from bacteria, is being made freely available ...

Research update: Genome editing becomes more accurate

Earlier this year, MIT researchers developed a way to easily and efficiently edit the genomes of living cells. Now, the researchers have discovered key factors that influence the accuracy of the system, an important step ...

Research sheds light on M.O. of unusual RNA molecules

(Phys.org) —The genes that code for proteins—more than 20,000 in total—make up only about 1 percent of the complete human genome. That entire thing—not just the genes, but also genetic junk and all the rest—is coiled ...

The genome's 3D structure shapes how genes are expressed

Scientists from Australia and the United States bring new insights to our understanding of the three-dimensional structure of the genome, one of the biggest challenges currently facing the fields of genomics and genetics. ...

Mapping translation sites in the human genome

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates—a process commonly known as translation. ...

The fight against genome parasites

In the gonads of animals, genome parasites such as transposons pose a serious threat to evolutionary fitness. With their ability to bounce around in the genome, they often cause dangerous mutations. To protect genomic integrity, ...

Single-cell sequencing

When studying any kind of population—people or cells—averaging is a useful, if flawed, form of measurement. According to the US Census Bureau, the average American household size in 2010 was 2.59. Of course, there are ...

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