How did life begin on Earth and could it exist elsewhere? Researchers at Simon Fraser University have isolated a genetic clue—an enzyme known as an RNA polymerase—that provides new insights about the origins of life. ...
Evolution
Mar 19, 2021
25
6444
Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands. No treatment is currently available to ...
Biotechnology
Mar 9, 2021
0
109
Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts—or edits—over time.
Biotechnology
Feb 23, 2021
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688
Gene expression is a highly regulated process that involves several steps. These include transcription of DNA instructions into RNA, removal of non-coding segments from the RNA message, and its subsequent translation into ...
Biotechnology
Feb 5, 2021
0
46
In a recent paper in RNA Biology, researchers show that mitochondria translocate their key RNA methyltransferase enzyme, TRMT1, into host cell nuclei in response to neural activity. This subcellular relocalization of key ...
A new study shows that many abnormalities in fragile X syndrome cells are related to glitches with one of the body's major quality control systems. Published in Nature Cell Biology, the research provides fresh insight into ...
Biotechnology
Feb 2, 2021
0
28
The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant type of RNA within cells, when resources are scarce and the bacteria Escherichia coli needs to slow ...
Biotechnology
Jan 22, 2021
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21
Macrophages—immune cells that both fight infections and fix the damage they cause—are often placed into two categories: those that increase inflammation (known as "M1") to attack, and those that decrease inflammation ...
Cell & Microbiology
Jan 21, 2021
0
130
A new Northwestern University-led study is unfolding the mystery of how RNA molecules fold themselves to fit inside cells and perform specific functions. The findings could potentially break down a barrier to understanding ...
Cell & Microbiology
Jan 15, 2021
0
1166
A long-running debate over how an important gene-silencing protein identifies its targets has been resolved by researchers at Massachusetts General Hospital (MGH). Their findings, reported in Nature Structural and Molecular ...
Molecular & Computational biology
Jan 4, 2021
0
111
