Scientists produce new antibiotics by gene editing

Scientists have discovered a new route to produce complex antibiotics exploiting gene editing to re-program pathways to future medicines urgently required to combat antimicrobial resistance, treat neglected diseases and tackle ...

Einstein was 'wrong,' not your science teacher

"Your teacher was wrong!" It's a phrase many a high school or university student has heard. As practicing and former science teachers, we have been challenged with this accusation before.

From rare soil microbe, a new antibiotic candidate

Demand for new kinds of antibiotics is surging, as drug-resistant and emerging infections are becoming an increasingly serious global health threat. Researchers are racing to reexamine certain microbes that serve as one of ...

Direct cloning method CAPTUREs novel microbial natural products

Microorganisms possess natural product biosynthetic gene clusters (BGCs) that may harbor unique bioactivities for use in drug development and agricultural applications. However, many uncharacterized microbial BGCs remain ...

Different paths to drug resistance in Leishmania

Two remarkable discoveries were today revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level.

Turning pathogens against each other to prevent drug resistance

Limiting a much-needed resource could pit pathogens against one another and prevent the emergence of drug resistance. New research demonstrates that harnessing competition among pathogens inside a patient could extend the ...

Review: PROTACs targeting epigenetic proteins

The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...

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