Over a decade ago, Shinya Yamanaka and Kazutoshi Takahashi made a discovery that would revolutionize biomedical research and trigger the field of regenerative medicine. They learned how to reprogram human adult cells into ...
Cell & Microbiology
Apr 10, 2018
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121
(Phys.org) —The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions ...
Cell & Microbiology
Mar 4, 2013
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Scientists from A*STAR's Genome Institute of Singapore (GIS) have discovered metabolic rejuvenation factors in eggs. This critical finding furthers our understanding of how cellular metabolism changes during aging, and during ...
Cell & Microbiology
Aug 13, 2015
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31
Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone ...
Cell & Microbiology
Feb 6, 2013
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A series of studies led by Monash University researcher Associate Professor Jose Polo have this week shed light on vital, yet previously unclear, aspects of cell reprogramming.
Cell & Microbiology
Dec 7, 2017
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57
Induced pluripotent stem cells (IPSCs) hold great promise in regenerative medicine, personalized medicine and drug discovery. However, while avoiding the ethical controversies associated with embryonic stem cells, they carry ...
Cell & Microbiology
May 24, 2017
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17
For their ability to differentiate into other cell types, the embryonic stem cells hold a large potential in the medical industry. Their use, however, poses ethical questions due to the fact that in order to obtain them, ...
Cell & Microbiology
Jun 10, 2015
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187
Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, ...
Cell & Microbiology
Apr 21, 2014
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In an advance that promises to facilitate research into stem cells and regenerative medicine, a RIKEN-led team has demonstrated a non-invasive method for tracking the chemical changes that accompany the reprogramming of somatic ...
Analytical Chemistry
Feb 12, 2021
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22
Damaged tissue, such as pancreas, heart, and neuronal tissue, which is regenerated to treat cardiovascular diseases, diabetes, or neurodegenerative diseases. This is one of the ambitious scenarios to which regenerative medicine ...
Cell & Microbiology
Aug 27, 2015
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