Genes that have roles in the same biological pathways change their rate of evolution in parallel, a finding that could be used to discover their functions, said a researcher at the University of Pittsburgh School of Medicine ...
Biotechnology
Feb 8, 2013
9
0
A unique gene-editing method that efficiently inserts DNA into genes located in dividing and non-dividing cells of living rats has been developed by a team of international researchers, including scientists from KAUST.
Biotechnology
Jan 30, 2017
0
12
Bats are a natural host for more than 100 viruses, some of which are lethal to people. These include Middle Eastern Respiratory Syndrome (MERS), Ebola and Hendra virus. These viruses are among the most dangerous pathogens ...
Ecology
Feb 23, 2016
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55
From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this ...
Molecular & Computational biology
Apr 15, 2021
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150
Leveraging a novel system designed to examine the double-strand DNA breaks that occur as a consequence of gene amplification during DNA replication, Whitehead Institute scientists are bringing new clarity to the causes of ...
Biotechnology
Jun 4, 2015
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17
Scientists at UMass Medical School have developed a strategy for editing and repairing a particular type of genetic mutation associated with microduplications using CRISPR-Cas9 and a seldom-used DNA repair pathway. Described ...
Biotechnology
Apr 4, 2019
0
164
Like a mechanic popping the hood of a car to get at a faulty engine, a tumor-suppressing protein allows cellular repair mechanisms to pounce on damaged DNA by overcoming a barrier to DNA access.
Cell & Microbiology
Jun 19, 2009
0
0
By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks—which drive every cellular process from protein ...
Cell & Microbiology
Oct 28, 2019
0
23
During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication ...
Biotechnology
May 4, 2015
0
39
A team of researchers from the University of Wisconsin have identified 46 genes in Escherichia coli that are necessary for its survival at exceptionally high levels of radiation. The paper appears ahead of print in the Journal ...
Biotechnology
Jul 21, 2014
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