New method to detect off-target effects of CRISPR

Since the CRISPR genome editing technology was invented in 2012, it has shown great promise to treat a number of intractable diseases. However, scientists have struggled to identify potential off-target effects in therapeutically ...

The tremendous supply of apple cultivars in Wyoming

A study out of the University of Wyoming sought to identify heritage apple cultivars planted in the state's homesteads, orchards, and nurseries from as early as 1870. Using microsatellite markers, surviving apple trees identified ...

CRISPR/Cas libraries open new avenues in cancer research

CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code. Using an entire library of zip codes, it is then possible ...

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