Mapping all of the chemical, or epigenetic, changes to chromosomes that affect which genes are turned on or off—and thus determine the fate of genomically identical cells in the body—usually requires a large amount of ...
Cell & Microbiology
May 22, 2013
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Environment is not the only factor in shaping regulatory patterns—and it might not even be the primary factor, according to a new Rice University study that looks at how cells' protein networks relate to a bacteria's genome.
Cell & Microbiology
May 21, 2013
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(Phys.org) —Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn't. In the journal Angewandte Chemie, a British team has now introduced a new method that makes ...
Biochemistry
Apr 25, 2013
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(Phys.org) —Sex determining genes in marsupials have shed some light on how the Y chromosome, which determines the male sex in humans, will quickly degenerate and eventually disappear, according to a world-renowned evolutionary ...
Biotechnology
Apr 3, 2013
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(Phys.org) —It is easier to copy something than to develop something new - a principle that was long believed to also apply to the evolution of genes. According to this, evolution copies existing genes and then adapts the ...
Biotechnology
Mar 26, 2013
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During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in ...
Biotechnology
Feb 28, 2013
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In each cell, thousands of regulatory regions control which genes are active at any time. Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna have developed a method that reliably detects these regions ...
Biotechnology
Jan 18, 2013
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(Phys.org)—Indiana University biologists Teiya Kijimoto, Justen Andrews and Armin Moczek say it's time to chalk another one up for doublesex, the master regulatory gene at the terminus of the sex determination pathway that ...
Plants & Animals
Nov 30, 2012
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Humans share over 90% of their DNA with their primate cousins. The expression or activity patterns of genes differ across species in ways that help explain each species' distinct biology and behavior.
Biotechnology
Nov 6, 2012
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Johns Hopkins researchers have succeeded in teaching computers how to identify commonalities in DNA sequences known to regulate gene activity, and to then use those commonalities to predict other regulatory regions throughout ...
Biotechnology
Nov 5, 2012
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