New roles for DNA-packaging proteins
How can human cells pack 3-meter-long DNA into their tiny nuclei and unpack it only where and when it is needed? This fascinating process is far from being completely understood.
How can human cells pack 3-meter-long DNA into their tiny nuclei and unpack it only where and when it is needed? This fascinating process is far from being completely understood.
Biotechnology
Feb 5, 2020
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Post-translational modification is the process whereby proteins are modified after their initial biosynthesis. Modification can take many forms, including enzymatic cleavage of the protein or the addition of sugars, lipids, ...
Plants & Animals
Feb 5, 2020
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10
IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could have implications ...
Biotechnology
May 16, 2019
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83
Scientists have captured the first "snapshot" of two proteins involved in delivering a bacterial stress-response master regulator to the cell's recycling machinery.
Molecular & Computational biology
Apr 11, 2019
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71
Pathological infertility is a condition affecting roughly 7 percent of human males, and among those afflicted, 10 to 15 percent are thought to have a genetic cause. However, pinpointing the precise genes responsible for the ...
Cell & Microbiology
Mar 26, 2019
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23
Researchers at the University of Dundee have provided important new insights into the regulation of cell division, which may ultimately lead to a better understanding of cancer progression.
Cell & Microbiology
Mar 14, 2019
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31
Transcription activator-like effector (TALE) proteins can be designed to bind to almost any selected DNA. Researchers now report that a TALE can displace another TALE protein from DNA in a highly polarized way – it can ...
Cell & Microbiology
Nov 26, 2018
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Proteins are the building blocks of the cell. They do most of the work and are essential for the structure, function and dynamic regulation of the cell and body's tissues and organs. Proteins rarely work alone, they interact, ...
Cell & Microbiology
Oct 26, 2018
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130
The development of an adult organism starts with a fertilized egg that differentiates into hundreds of specialized cell types comprising tissues and organs. How these cell fate changes happen is a subject of research interest. ...
Cell & Microbiology
Oct 3, 2018
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9
Walter and Eliza Hall Institute researchers have made a surprise discovery about how subtle changes in the way cell survival is regulated during embryonic development can have drastic health implications.
Cell & Microbiology
Sep 19, 2018
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19