By reproducing in the laboratory the complex interactions that cause human genes to turn on inside cells, Duke University bioengineers have created a system they believe can benefit gene therapy research and the burgeoning ...
Biotechnology
Feb 3, 2013
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Transmitting from one generation to the next the genetic message encoded in DNA is a well-understood concept in biology. There is now increasing awareness that chemical modifications of DNA and associated proteins are also ...
Biochemistry
Jan 24, 2013
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In each cell, thousands of regulatory regions control which genes are active at any time. Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna have developed a method that reliably detects these regions ...
Biotechnology
Jan 18, 2013
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Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate the process by which ...
Cell & Microbiology
Jan 17, 2013
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(Phys.org)—A research team of scientists from EMBL Grenoble and the IGBMC in Strasbourg, France, have, for the first time, described in molecular detail the architecture of the central scaffold of TFIID: the human protein ...
Cell & Microbiology
Jan 7, 2013
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(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research and the Biozentrum of the University of Basel have published an important proof-of-principle study showing that a computational model can ...
Biotechnology
Dec 4, 2012
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(Phys.org)—Indiana University biologists Teiya Kijimoto, Justen Andrews and Armin Moczek say it's time to chalk another one up for doublesex, the master regulatory gene at the terminus of the sex determination pathway that ...
Plants & Animals
Nov 30, 2012
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Our master circadian clock resides in a small group of about 10'000 neurons in the brain, called the suprachiasmatic nucleus. However, similar clocks are ticking in nearly all cells of the body, as demonstrated by the group ...
Cell & Microbiology
Oct 26, 2012
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(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the cell. Supported ...
Cell & Microbiology
Sep 7, 2012
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(Phys.org)—Scientists at North Carolina State University have discovered a phenomenon never seen before in plants while studying molecular changes inside tree cells as wood is formed.
Biotechnology
Aug 23, 2012
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