Researchers at the UAB have determined the structure of amyloid fibers formed by the protein hnRNPDL-2, implicated in limb-girdle muscular dystrophy type 3, using high-resolution cryo-electron microscopy (cryo-EM). They have ...
Biotechnology
Feb 3, 2023
0
68
An international research group has for the first time reconstructed ancestors dating back 2.6 billion years of the well-known CRISPR-Cas system, and studied their evolution over time. The results suggest that the revitalized ...
Cell & Microbiology
Jan 4, 2023
0
1254
Investigators have identified a novel role for an intracellular trafficking pathway in regulating epidermal developmental processes, which could serve as a future therapeutic target for inflammatory skin diseases, according ...
Cell & Microbiology
Dec 12, 2022
0
14
Ribosomes, the tiny protein-producing factories within cells, are ubiquitous and look largely identical across the tree of life. Those that keep bacteria chugging along are, structurally, not much different from the ribosomes ...
Cell & Microbiology
Dec 8, 2022
0
18
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
0
80
Researchers are a step closer to understanding how Parkinson's disease develops and progresses thanks to chemical biological tools developed at Simon Fraser University.
Biochemistry
Jul 13, 2022
0
122
A new stem cell study by KAUST researchers helps to explain a rare genetic disease called Wiskott-Aldrich syndrome (WAS), yielding molecular clues that could lead to new treatments for a devastating immune deficiency disorder. ...
Cell & Microbiology
Jul 6, 2022
0
45
Many of us try to repress the thought of them, while others have come to accept them. Whatever your take on parasites is, they can tell scientists a lot about ecology, health and the environment.
Ecology
Jun 6, 2022
0
31
Protein complexes that play a critical role in launching an immune response assemble in droplets that form within the liquid environment in cells much like oil droplets in water, UT Southwestern scientists report in a new ...
Cell & Microbiology
Jun 3, 2022
0
35
An organism's genome could be compared to a complex system of instructions that allows it not only to develop, but also to carry out all the activities essential to its survival. To do this, this genome needs to be expressed ...
Molecular & Computational biology
Dec 3, 2021
0
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