New mRNA technology turns cells into long-lasting drug factories

A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan ...

Abnormal RNA gums up the works in brain cells, shows study

Our DNA contains four types of molecules, adenine, cytosine, thymine, and guanine—called nucleotides or bases—running along the strands that make up our chromosomes. Since there are only four, it is not unusual to find ...

Modified nucleotides used in COVID-19 vaccines work as designed

The remarkable effectiveness of mRNA vaccines against SARS-CoV-2 has generated much interest in synthetic mRNA therapeutics for treating and preventing disease. But some basic science questions have remained about whether ...

How calcium ions get into the cellular power stations of plants

Calcium is a very special nutrient. In the cells of most living beings calcium ions function as so-called second messengers to transmit important signals. The same applies equally to animal, plant and fungal cells. Through ...

Developing tools to visualize DNA repair as never before

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...

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