Microneedles for therapeutic gene delivery

There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections. The therapies work by delivering genes into the patients' cells, which then ...

New understanding of CRISPR-Cas9 tool could improve gene editing

Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy. But CRISPR-Cas9 also has spawned other potentially powerful DNA manipulation tools that could help fix genetic ...

Proteins—and labs—coming together to prevent Rett syndrome

New discoveries about the disruption of condensates in the neurodevelopmental disorder Rett syndrome provide insights into how cells compartmentalize chromosomes as well as new potential paths for therapies.

Researchers study protein biosynthesis in bacteria

Researchers of the University of Bayreuth and the Columbia University in New York reported groundbreaking findings on protein biosynthesis in bacteria in the journal iScience. The small protein NusG links the two large molecular ...

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