Elementary cytoskeleton protein is different in parasites and represents a starting point for a possible new therapy against malaria infections. Researchers from the Heidelberg University Hospital, the Centre for Molecular ...
Cell & Microbiology
Jul 20, 2018
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11
When hemoglobin undergoes just one mutation, these protein complexes stick to one another, stacking like Lego blocks to form long, stiff filaments. These filaments, in turn, elongate the red blood cells found in sickle-cell ...
Cell & Microbiology
Aug 23, 2017
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7
One of the hallmarks of Alzheimer's disease is the presence of neurofibrillary tangles in the brain. These tangles, made of tau proteins, impair neurons' ability to function normally and can cause the cells to die.
Biochemistry
May 27, 2022
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93
Many amphibians and fish are able to change their color in order to better adapt to their environment. Munich-based scientists have now investigated the molecular mechanisms in the cytoskeleton necessary for this and revealed ...
Biotechnology
Feb 12, 2020
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25
Actin filaments—protein structures critical to living movement from single cells to animals—have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ...
Cell & Microbiology
Jun 8, 2023
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133
A team of researchers of the International School for Advanced Studies (SISSA) of Trieste and of University of Cambridge have devised a method to reduce the time used to simulate how proteins take on their signature three-dimensional ...
Biochemistry
May 8, 2013
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0
Actin is among the most abundant proteins in cells, and it has many jobs—from giving the cell its very shape and structure to managing networks of proteins crucial to numerous cellular functions. Without it, the fragile ...
Cell & Microbiology
Oct 26, 2020
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30
Research conducted in the University of Helsinki may help in developing specific inhibitors that would slow down actin-dependent movement of cancer cells.
Cell & Microbiology
May 17, 2018
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(Phys.org)—A new model system of the cellular skeletons of living cells is akin to a mini-laboratory designed to explore how the cells' functional structures assemble. A paper about to be published in European Physical ...
General Physics
Sep 19, 2012
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0
Protein filament systems within cells are subject to constant reorganization, which is in part mediated by the actions of motor proteins. LMU researchers have now shown that motor-driven movements can propagate through such ...
Molecular & Computational biology
Jan 9, 2020
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