Advances in intracellular spaces with de novo designed peptide

Scientists at Tokyo Institute of Technology (Tokyo Tech) have set out to harness the potential of self-assembling peptides (SAPs) in intracellular spaces. They present a de novo designed peptide, Y15, which displays a strong ...

How a large protein complex assembles in a cell

A team of ETH researchers led by Karsten Weis has developed a method that allows them to study the assembly process for large protein complexes in detail for the first time. As their case study, the biologists chose one of ...

Structural clues for influenza virus assembly and disassembly

The influenza A virus is surrounded by a lipid bilayer that forms the outermost layer much like the plasma membranes on our own cells. Immediately under this lipid bilayer is a dense protein layer formed from M1 matrix protein. ...

Gold adds the shine of reversible assembly to protein cages

Protein cages—capsule-like structures made up of numerous protein molecules—perform roles in nature that have inspired their application in areas such as drug delivery. Their controlled assembly is therefore of particular ...

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