Some anti-inflammatory drugs affect more than their targets

Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Their finding suggests that, if taken at higher-than-approved doses ...

Two new weapons in the battle against bacteria

Proteases are vital proteins that serve for order within cells. They break apart other proteins, ensuring that these are properly synthesized and decomposed. Proteases are also responsible for the pathogenic effects of many ...

Microbes help beetles defeat plant defenses

Some symbiotic bacteria living inside Colorado potato beetles can trick plants into reacting to a microbial attack rather than that of a chewing herbivore, according to a team of Penn State researchers who found that the ...

Molecular discovery puts cancer treatment in a new perspective

Researchers from the University of Copenhagen and the National Institutes of Health have obtained ground-breaking new knowledge about proteases - important enzymes which, among other things, play a role in the development ...

Enzyme helps cancer cells avoid genetic instability

Cancer cells are resourceful survivors with plenty of tricks for staying alive. Researchers have uncovered one of these stratagems, showing how cells lacking the tumor suppressor BRCA1 can resume one form of DNA repair, sparing ...

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