An easier way to manipulate malaria genes

Plasmodium falciparum, the parasite that causes malaria, has proven notoriously resistant to scientists' efforts to study its genetics. It can take up to a year to determine the function of a single gene, which has slowed ...

Researchers capture 'key' to deadly malaria infection

An international team led by Institute researchers has visualised the unique molecular 'key' used by the world's deadliest malaria parasite, Plasmodium falciparum, to enter and infect human blood cells.

How malaria tricks the immune system

Global efforts to eradicate malaria are crucially dependent on scientists' ability to outsmart the malaria parasite. And Plasmodium falciparum is notoriously clever: It is quick to develop resistance against medications and ...

MMV malaria box phenotyped against plasmodium and toxoplasma

A Singapore-India collaborative research project has completed phenotypic screening of MMV Malaria Box, a large collection of potent chemical inhibitors against pathogenic parasites Toxoplasma gondii and Plasmodium falciparum, ...

Catching malaria evolution in the act

Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques ...

How the malaria parasite defends itself from fever

A gene called PfAP2-HS allows the malaria parasite to defend itself from adverse conditions in the host, including febrile temperatures, according to a new study led by the Barcelona Institute for Global Health (ISGlobal), ...

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