Harnessing AI to discover new drugs inspired by nature

Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated. Moreover, AI helps to find molecules that have the same effect ...

How cells 'read' artificial ingredients tossed into genetic recipe

If the genome is the recipe of life, base pairs are the individual ingredients listed. These chemical structures form DNA, and every living organism on Earth has just four. The specific arrangements of these four base pairs—A, ...

Wider applications for the 'unboil an egg' machine

Wider clean chemistry applications of the extraordinary Vortex Fluidic Device—invented by Flinders University's Professor Colin Raston—are likely in the wake of new research that has been published outlining the seemingly ...

Using CRISPR to lower cholesterol levels in monkeys

A team of researchers from Verve Therapeutics and the Perelman School of Medicine at the University of Pennsylvania has developed a CRISPR gene-editing technique that lowered the levels of cholesterol in the blood of test ...

Genome mining leads to a new type of peptide prenylation

Researchers from NUS used a genome mining approach to identify a new cyclic peptide (tolypamide) derived from a cyanobacterium. The biosynthesis of tolypamide features a new type of enzyme that is able to prenylate a range ...

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