The Wnt/β-catenin signaling pathway and microRNA 335 are instrumental in helping form differentiated progenitor cells from stem cells. These are organized in germ layers and are thus the origin of different tissue types, ...
Cell & Microbiology
Jan 23, 2014
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VIB scientists associated to the UGent have developed a mouse model that can advance the research on iPS cells to the next step.
Cell & Microbiology
Feb 21, 2013
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According to researchers at Boston Children's Hospital, stem cells that strongly express a gene called WNT3 are biased to develop into cells and tissues including pancreas, liver and bladder. This discovery suggests that ...
Cell & Microbiology
Jun 4, 2013
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The death of insulin-producing beta cells in the pancreas is a core defect in diabetes. Scientists in Italy and Texas now have discovered a new way that these cells die — by toxic imbalance of a molecule secreted by ...
Biochemistry
Feb 25, 2011
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In 2008 the Spanish company PharmaMar, dedicated to developing marine-derived drugs against cancer, isolated a promising substance called pipecolidepsin A from the sponge Homophymia lamellosa collected off the coast of Madagascar. ...
Biochemistry
Sep 4, 2013
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Despite the hubbub about pluripotent stem cells' potential applications, when it comes time to introduce products into patients, the stem cells are actually impurities that need to be removed.
Biotechnology
Aug 17, 2016
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New research successfully reverses epilepsy-associated pathology by using a sophisticated single-cell modeling paradigm to examine abnormal cell behavior and identify the optimal modulation of channel activity. The study, ...
Biochemistry
Oct 18, 2011
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Planarians are known as masters of regeneration: they can re-build any part of their bodies after amputation. This ability relies on a large number of pluripotent stem cells. To further investigate the mechanisms that enable ...
Cell & Microbiology
Jun 5, 2014
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There are two types of stem cell considered promising sources of cells for regenerative therapies: ES and iPS cells. Recent data indicate these cells are molecularly different, raising the possibility that cells derived from ...
Cell & Microbiology
May 2, 2011
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Researchers have found a way in mice to convert another type of pancreas cell into the critical insulin-producing beta cells that are lost in those with type I diabetes. The secret ingredient is a single transcription factor, ...
Biochemistry
Aug 6, 2009
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