Not unlike looking for the proverbial needle in a haystack, a team of Michigan State University researchers have found a gene that could be key to the development of stem cells – cells that can potentially save millions ...
Cell & Microbiology
Jul 17, 2014
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From obesity to substance abuse, from anxiety to cancer, genetically modified mice are used extensively in research as models of human disease. Researchers often spend years developing a strain of mouse with the exact genetic ...
Biotechnology
Jun 26, 2013
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(Phys.org)—A research team from the University of California has identified two reprogramming events that occur during the development of oocytes and sperm leading to the formation of gametes in humans. In studying aborted ...
Researchers reporting in the April 27 issue of the journal Cell have devised a new and improved method for producing genetically modified animals for use in scientific research. The method relies on haploid embryonic stem ...
Cell & Microbiology
Apr 26, 2012
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Most cells rely on structural tethers to position chromosomes in preparation for cell division. Not so oocytes. Instead, a powerful intracellular stream pushes chromosomes far-off the center in preparation for the highly ...
Cell & Microbiology
Aug 28, 2011
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University of Pennsylvania biologists studying human reproduction have identified what is likely the major contributing factor to the maternal age-associated increase in aneuploidy, the term for an abnormal number of chromosomes ...
Cell & Microbiology
Sep 8, 2010
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Biologists at the University of Pennsylvania studying oocytes in mice, the immature egg cells necessary for sexual reproduction, have demonstrated an unusual behavior in microRNA, or miRNA, activity that may be the first ...
Cell & Microbiology
Feb 3, 2010
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Safe and high-quality fertility preservation is of growing significance for women in clinical trials. Current primary methods for cryopreserving human oocytes are slow freezing and vitrification, but existing techniques pose ...
Bio & Medicine
May 15, 2024
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Elaborate observations reveal the structural specialization within an epithelial layer covering oocytes in the Japanese pill-millipede, Hyleoglomeris japonica, considered absent in Myriapoda. Comparing this result with previous ...
Plants & Animals
May 7, 2024
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Human development starts from the fertilization of a fully matured oocyte. Oocyte maturation, fertilization, and early embryo development before zygotic activation is characterized by the absence of new transcription from ...
Cell & Microbiology
Jan 19, 2023
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