Researchers reveal DNA repair mechanism

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

How TFIIH uses XPG to located damaged DNA

Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.

Feline genetics help pinpoint first-ever domestication of cats

Nearly 10,000 years ago, humans settling in the Fertile Crescent, the areas of the Middle East surrounding the Tigris and Euphrates rivers, made the first switch from hunter-gatherers to farmers. They developed close bonds ...

Artificial intelligence folds RNA molecules

For the function of many biomolecules, their three-dimensional structure is crucial. Researchers are therefore not only interested in the sequence of the individual building blocks of biomolecules, but also in their spatial ...

Building blocks for RNA-based life abound at center of our galaxy

Nitriles, a class of organic molecules with a cyano group—that is, a carbon atom bound with a triple unsaturated bond to a nitrogen atom—are typically toxic. But paradoxically, they are also a key precursor for molecules ...

Crystal study may resolve DNA mystery

When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.

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