Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report that they have identified a previously undiscovered trigger mechanism for a quality control checkpoint at the very end of the cell division ...
Cell & Microbiology
Nov 22, 2010
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A team led by Naoko Imamoto of the RIKEN Advanced Science Institute in Wako, Japan, has uncovered processes governing the formation of functionally important structures called nuclear pore complexes (NPCs) in dividing human ...
Cell & Microbiology
Oct 18, 2010
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Fluorescent microscopy makes use of molecules, such as green fluorescent protein (GFP), that emit colored light when illuminated with light of a specific wavelength. Molecules like GFP can be used to label proteins of interest ...
Biochemistry
Sep 21, 2010
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(PhysOrg.com) -- UC Berkeley researchers Karsten Weis, Jan Liphardt, and colleagues have used fluorescent probes called quantum dots to determine which molecules get into the nucleus via its nano-pores and which get kicked ...
Bio & Medicine
Sep 2, 2010
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(PhysOrg.com) -- Biologists led by associate professor Thomas Schwartz (MIT) have worked out a rudimentary architectural plan for the nuclear pore complex (NPC), the gatekeeper of the cell's nucleus.
Cell & Microbiology
Oct 27, 2009
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When it comes to the two basic types of cells, prokaryotes and eukaryotes, compartmentalization is everything. Prokaryotes are evolutionarily ancient cells that only have a membrane surrounding their outer boundary, while ...
Biochemistry
Oct 6, 2009
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(PhysOrg.com) -- The NPC is the only way in or out of a cell's nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further ...
Cell & Microbiology
Sep 29, 2009
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(PhysOrg.com) -- Computational biochemist Frank Alber compares determining the architecture of a macromolecular machine to solving a jigsaw puzzle.
Biochemistry
Aug 19, 2009
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(PhysOrg.com) -- To protect their DNA, cells in higher organisms are very choosy about what they allow in and out of their nuclei, where the genes reside. Guarding access is the job of transport machines called nuclear pore ...
Cell & Microbiology
Aug 18, 2009
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(PhysOrg.com) -- For perhaps 1.8 billion years after life first emerged on Earth, a sort of evolutionary writer’s block stalled the development of organisms more complicated than single cells. Then, a burst of experimental ...
Biochemistry
Jul 13, 2009
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