Researchers identify drug compounds that can reduce prion protein levels in infected cells
Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.
Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.
Biochemistry
May 15, 2024
0
30
Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal ...
Biochemistry
Aug 8, 2022
0
36
Crotoxin, extracted from the venom of the South American rattlesnake Crotalus durissus terrificus, has been studied for almost a century for its analgesic, anti-inflammatory and antitumor activities and as an even more powerful ...
Bio & Medicine
Feb 17, 2020
0
659
An international team of researchers has used nanoparticles to deliver a drug—one that previously failed in clinical trials for pain—into specific compartments of nerve cells, dramatically increasing its ability to treat ...
Bio & Medicine
Nov 4, 2019
2
1095
A new computational model successfully predicts how daily pain sensitivity rhythms affect pain processing, both in healthy adults and in people with neuropathic pain. Jennifer Crodelle of New York University and colleagues ...
Molecular & Computational biology
Jul 11, 2019
0
0
Associate Professor Greg Neely and his team of pain researchers in the Charles Perkins Centre have found compelling evidence that insects feel persistent pain after injury.
Plants & Animals
Jul 11, 2019
4
282
Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins ...
Biochemistry
Apr 5, 2017
0
109
At present there are no consistently safe and effective methods for the treatment of headshaking in horses. The condition, a neuropathic facial pain syndrome, often leaves affected horses impossible to ride and dangerous ...
Plants & Animals
Jan 6, 2015
0
42
Scientists reported today they have created at least five new experimental substances—based on a tiny protein found in cone snail venom—that could someday lead to the development of safe and effective oral medications ...
Materials Science
Mar 16, 2014
0
1