Shaping the social networks of neurons

The three proteins teneurin, latrophilin and FLRT hold together and bring neighboring neurons into close contact, enabling the formation of synapses and the exchange of information between the cells. In the early phase of ...

Researchers decode the circuitry of neuromuscular organoids

The Gouti lab from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) has developed functional neuromuscular organoids (NMOs) that self-organize into spinal cord neurons and muscle tissue. ...

'Census' in the zebrafish's brain

The zebrafish is a master of regeneration: If brain cells are lost due to injury or disease, it can simply reproduce them—contrary to humans, where this only happens in the fetal stage. However, the zebrafish is evolutionarily ...

A timekeeper for siesta

Circadian clocks must be flexible and they must be able to adapt to varying environmental conditions. Otherwise, it would be impossible for living beings to change their patterns of activity when the days get shorter again ...

The sleep neuron in threadworms is also a stop neuron

Wagner Steuer Costa in the team of Alexander Gottschalk, Professor for Molecular Cell Biology and Neurobiochemistry, discovered the sleep neuron RIS a few years ago by coincidence—simultaneously with other groups. To understand ...

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