(PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism ...
Biotechnology
Feb 20, 2012
0
0
(PhysOrg.com) -- For the first time, a new computational method allows researchers to identify which specific molecular mechanisms are altered by genetic mutations in proteins that lead to disease. And they can apply this ...
Biotechnology
Jan 19, 2012
0
0
For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes ...
Biochemistry
Dec 11, 2011
0
0
Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...
Cell & Microbiology
Nov 23, 2011
1
0
(PhysOrg.com) -- Scientists of many varied backgrounds have been hard at work in recent years trying to figure out a way to control the intricate processes that go on in cells so as to allow them to manipulate them to do ...
Knowledge about the development of the nervous system is of the greatest importance for us to understand the function of the brain and brain disorders. Researchers at Uppsala University have examined the key step when genes ...
Cell & Microbiology
Nov 7, 2011
0
0
Over four billion years of evolution, plants and animals grew far more complex than their single-celled ancestors. But a new comparison of proteins shared across species finds that complex organisms, including humans, have ...
Evolution
May 18, 2011
8
0
(PhysOrg.com) -- RNA plays a critical role in directing the creation of proteins, but there is more to the life of an RNA molecule than simply carrying DNA's message. One can imagine that an RNA molecule is born, matures, ...
Biotechnology
Apr 24, 2011
0
0
Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists ...
Cell & Microbiology
Mar 20, 2011
0
0
Like cats, human cells have a finite number of lives-once they divide a certain number of times (thankfully, more than nine) they change shape, slow their pace, and eventually stop dividing, a phenomenon called "cellular ...
Cell & Microbiology
Oct 3, 2010
0
0
