Stem cell clues uncovered

Proper tissue function and regeneration is supported by stem cells, which reside in so-called niches. New work from Carnegie's Yixian Zheng and Haiyang Chen identifies an important component for regulating stem cell niches, ...

Fly dreams and the boundaries of evolutionary science

In 2002, Secretary of state Donald Rumsfeld made a statement regarding weapons of mass destruction that today is still well known. He famously parsed the evidence (or lack thereof) into "known knowns, known unknowns, and ...

'Soft' CRISPR may offer a new fix for genetic defects

Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their ...

Evolution silences harmful mutations

Sometimes so-called synonymous mutations occur in DNA. These do not lead to a change in the protein sequence but which may still have major negative effects on the ability of bacteria to survive. New research from Uppsala ...

Large-scale study of genetic data shows humans still evolving

In a study analyzing the genomes of 210,000 people in the United States and Britain, researchers at Columbia University find that the genetic variants linked to Alzheimer's disease and heavy smoking are less frequent in people ...

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