Modern humans evolutionarily split from our chimpanzee ancestors nearly 7 million years ago, yet we are continuing to evolve. 155 new genes have been identified within the human lineage that spontaneously arose from tiny ...
Evolution
Dec 20, 2022
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380
Neuromuscular disorders affect millions of people worldwide. Now a discovery made at the Montreal Clinical Research Institute of Montreal (IRCM) opens the door to the development of targeted therapies.
Cell & Microbiology
Dec 19, 2022
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10
WNT signaling is crucial for the development of organisms and the maintenance of tissue homeostasis, since the WNT messengers are involved in a variety of cellular functions. In skeletal muscle, for example, they can increase ...
Cell & Microbiology
Dec 13, 2022
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10
For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine. This new tool of molecular biology has its origins in an ancient bacterial immune system. It protects bacteria from ...
Biotechnology
Nov 25, 2022
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178
Researchers from Tokyo Metropolitan University have developed a way to characterize the force generated by contracting myotubes, precursors to skeletal muscle fiber, combining electrostimulation and analysis of wrinkles in ...
Biochemistry
Sep 5, 2022
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95
The development of an embryo is a well-orchestrated string of processes, ensuring correct formation and positioning of vital organs of the growing organism. At the molecular level, these processes are controlled in a precise ...
Molecular & Computational biology
Jun 29, 2022
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146
Dystroglycans on epithelial cell surfaces interact with the extracellular matrix via long sugar chains (called matriglycans), and they are responsible for cell adhesion. Abnormalities in the formation of matriglycans can ...
Biochemistry
Jun 27, 2022
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6
A group led by Dr. Minas Nalbandian has established an atlas of human pluripotent stem cell-derived muscle progenitor cells (hiPSC-MuPCs) and found the heterogeneity in hiPSC-MuPCs.
Cell & Microbiology
Apr 27, 2022
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3
In proof-of-concept experiments, Johns Hopkins Medicine scientists say they have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, potentially advancing ...
Cell & Microbiology
Apr 21, 2022
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94
Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, ...
Molecular & Computational biology
Mar 14, 2022
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288
