Aurora A may contribute to kidney disease

The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology.

Rare New Mexico meadow jumping mouse populations discovered

Biologists who spent weeks in three New Mexico national forests searching for signs of an elusive, endangered mouse that looks somewhat like a tiny kangaroo have found what they call irrefutable evidence that it still lives ...

Carcinogenic mechanism of incomplete cell reprogramming in vivo

A research team led by the group of Professor Yasuhiro Yamada, Center for iPS Cell Research and Application (CiRA), Kyoto University, has discovered that when cells are subjected to incomplete reprogramming in vivo, epigenetic ...

Production of iPS cells: Discovery of the fifth element

Since 2006, research has succeeded in generating, from specialised adult cells, induced pluripotent cells (iPS cells), with huge potential applications, particularly for regenerative medicine. However, the process has still ...

New advances in stem-cell derived mouse embryo model

Just two weeks after announcing the development of a mouse embryo model, complete with beating hearts and the foundations for a brain and other organs, from mouse stem cells, researchers in the laboratory of Magdalena Zernicka-Goetz, ...

Mapping trees can help count endangered lemurs

The vast majority of lemur species are on the edge of extinction, experts warn. But not every lemur species faces a grim future. There may be as many as 1.3 million white-fronted brown lemurs still in the wild, for example, ...

A knockout resource for mouse genetics

An international consortium of researchers report today in Nature that they have knocked out almost 40 per cent of the genes in the mouse genome. The completed resource will power studies of gene activity in models of human ...

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