Fast track to mouse modeling

What genes are responsible for the development of breast cancer? What are the brain cell mutations that lead to the onset of Alzheimer's? To find new therapies, scientists have to understand how diseases are triggered at ...

Turning point of a lifetime

For the first time, scientists can observe the first two to three days of a mouse embryo's life, as it develops from a fertilised egg up to the stage when it would implant in its mother's uterus, thanks to a new light sheet ...

Bovine embryos as a model for early human development

The mechanisms that underlie early embryonic development in humans and cattle are very similar. Therefore, LMU researchers argue that bovine embryos might well be a better model for early human development than the mouse ...

Unearthing King Tet: Key protein influences stem cell fate

Take a skin cell from a patient with Type 1 diabetes. Strip out everything that made it a skin cell, then reprogram it to grow into a colony of pancreatic beta cells. Implant these into your patient and voilà! She's producing ...

Study sheds light on genetic 'clock' in embryonic cells

As they develop, vertebrate embryos form vertebrae in a sequential, time-controlled way. Scientists have determined previously that this process of body segmentation is controlled by a kind of "clock," regulated by the oscillating ...

First 'cell map' of 20,000 cells in mammalian embryo

Scientists at the Wellcome—MRC Cambridge Stem Cell Institute have used cutting-edge technology to profile over 20,000 individual cells to produce the first 'cell map' describing all the major cell types present at the early ...

Researchers piggyback to safer reprogrammed stem cells

Austin Smith and his research team at the Centre for Stem Cell Research in Cambridge have just published in the journal Development a new and safer way of generating pluripotent stem cells - the stem cells that can give rise ...

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