Why synonymous mutations are not always silent

New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...

A 'door' into the mitochondrial membrane

Mitochondria—the organelles responsible for energy production in human cells—were once free-living organisms that found their way into early eukaryotic cells over a billion years ago. Since then, they have merged seamlessly ...

Armored worm reveals the ancestry of three major animal groups

An international team of scientists, including from the Universities of Bristol and Oxford, and the Natural History Museum, have discovered that a well-preserved, fossilized worm dating from 518 million years ago resembles ...

Using nanopores to detect epigenetic changes faster

Changes known as epigenetic modifications play an important role in cancer development. Being able to analyze them quickly and reliably could contribute significantly to the further development of personalized therapy. A ...

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