DNA with a twist: Discovery could further antibiotic drug development
Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments.
Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments.
Biochemistry
Nov 22, 2018
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Researchers at The University of Texas at Dallas (UTD), led by Dr. Lee Bulla, have demonstrated for the first time the selective cytotoxicity of Bacillus thuringiensis subsp. israelensis Cry4B toxin is mediated by BT-R3. ...
Cell & Microbiology
Aug 24, 2013
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Patescibacteria are a group of puzzling, tiny microbes whose manner of staying alive has been difficult to fathom. Scientists can cultivate only a few types, yet these bacteria are a diverse group found in many environments.
Cell & Microbiology
Sep 7, 2023
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Biochemists at The Scripps Research Institute (TSRI) have discovered a genetic sequence that can alter its host gene's activity in response to cellular energy levels. The scientists have found this particular energy-sensing ...
Biochemistry
Oct 21, 2012
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Better tools for manipulating DNA in the laboratory may soon be possible with newly discovered deoxyribozymes (catalytic DNA) capable of cleaving single-stranded DNA, researchers at the University of Illinois say.
Cell & Microbiology
Aug 16, 2009
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Organisms employ a fascinating array of strategies to identify and restrain invasive pieces of foreign DNA, such as those introduced by viruses. For example, many viruses produce double-stranded (ds)RNA during their life ...
Biotechnology
Jun 26, 2012
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(PhysOrg.com) -- A research team has made precise measurements of where and how RNA polymerase encounters obstacles while it reads nucleosomal DNA.
Cell & Microbiology
May 14, 2010
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The devastating disease Huonglongbing, or citrus greening, looms darkly over the United States, threatening to wipe out the nation's citrus industry, whose fresh fruit alone was valued at more than $3.4 billion in 2012.
Ecology
Sep 25, 2013
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Scientists from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), Lawrence Berkeley National Laboratory, and the University of California, San Diego have developed a set of molecular tools that provide important ...
Feb 12, 2009
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A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his ...
Cell & Microbiology
Aug 21, 2013
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