Chemists make cellular forces visible at the molecular scale

Scientists have developed a new technique using tools made of luminescent DNA, lit up like fireflies, to visualize the mechanical forces of cells at the molecular level. Nature Methods published the work, led by chemists ...

RNA information transfer could be used in repairing DNA

Genomes are routinely subjected to DNA damage. But most cells have DNA repair systems that enforce genome stability and, ideally, prevent diseases like cancer. The trouble gets serious when these systems break down. When ...

Researchers discover how enzyme protects cells from DNA damage

A research team from Mount Sinai has unraveled for the first time the three-dimensional structure and mechanism of a complex enzyme that protects cells from constant DNA damage, opening the door to discovery of new therapeutics ...

Molecular forces: The surprising stretching behavior of DNA

When large forces act on a heavy beam, for example, in bridge construction, the beam will be slightly deformed. Calculating the relationship between forces, internal stresses and deformations is one of the standard tasks ...

Molecular 'tails' are secret ingredient for gene activation

It might seem as though humans have little in common with the lowly yeast cell. Humans have hair, skin, muscles, and bones, among other attributes. Yeast have, well, none of those things.

The Y chromosome is disappearing: What will happen to men?

The Y chromosome may be a symbol of masculinity, but it is becoming increasingly clear that it is anything but strong and enduring. Although it carries the "master switch" gene, SRY, that determines whether an embryo will ...

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