Do our mitochondria run at 50 degrees C?

Our body temperature is held at a fairly steady 37.5°C, and the assumption has always been that most of our physiological processes take place at this temperature. The heat needed to maintain this temperature in the face ...

Lysosome to mitochondria communication regulates longevity

As people get older, they often feel less energetic, mobile or active. This may be due in part to a decline in mitochondria, the tiny powerhouses inside of our cells, which provide energy and regulate metabolism. In fact, ...

Researchers discover mitochondria-to-nucleus messenger protein

Researchers have identified a protein, G-Protein Pathway Suppressor 2 (GPS2), that moves from a cell's mitochondria to its nucleus in response to stress and during the differentiation of fat cells. While proteins with similar ...

When less is more: How mitochondrial signals extend lifespan

In making your pro-longevity resolutions, like drinking more red wine and maintaining a vibrant social network, here's one you likely forgot: dialing down your mitochondria. It turns out that slowing the engines of these ...

'Anti-Atkins' low protein diet extends lifespan in flies

Flies fed an "anti-Atkins" low protein diet live longer because their mitochondria function better. The research, done at the Buck Institute for Age Research, shows that the molecular mechanisms responsible for the lifespan ...

New aging-related molecular pathway discovered

A collaborative project between the labs of Maulik Patel, assistant professor of biological sciences, and Kris Burkewitz, assistant professor of cell and developmental biology, has identified a new molecular pathway that ...

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