At the heart of brain diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and Parkinson's disease is protein misfolding, in which distorted proteins are unable to perform their normal functions. At ...
Cell & Microbiology
Jan 16, 2014
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Rice University researchers have discovered a hidden symmetry in the chemical kinetic equations scientists have long used to model and study many of the chemical processes essential for life.
Biochemistry
Apr 30, 2020
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Yeast cells can sometimes reverse the protein misfolding and clumping associated with diseases such as Alzheimer's, according to new research from the University of Arizona.
Cell & Microbiology
Dec 9, 2014
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Scientists from Texas are batty over a new discovery which could lead to the single most important medical breakthrough in human history -- significantly longer lifespans. The discovery, featured on the cover of the July ...
Biochemistry
Jun 30, 2009
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When the body loses its ability to fold proteins into the correct shapes, the result can be irreversible and tragic. The accumulation of unfolded or misfolded proteins in the brain causes many devastating neurodegenerative ...
Biochemistry
Feb 26, 2016
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For the first time, scientists have developed a computer simulation of how clumps of defective proteins in neurodegenerative diseases like Alzheimer's spread through the brain, much of the time in stealth mode, over as long ...
General Physics
Oct 12, 2018
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155
By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein.
Biochemistry
May 20, 2024
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46
Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer's, Parkinson's, and Huntington's diseases. Cells work constantly to eliminate misfolded ...
Cell & Microbiology
Apr 20, 2023
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121
A large number of illnesses stem from misfolded proteins, molecules composed of amino acids. Researchers at the University of Zurich have now studied protein misfolding using a special spectroscopic technique. Misfolding, ...
Cell & Microbiology
May 31, 2011
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"Protein misfolding" diseases such as cystic fibrosis and Alzheimer's may be seriously exacerbated by the body's own response against that misfolding, according to a new study led by scientists at The Scripps Research Institute ...
Cell & Microbiology
Nov 18, 2014
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