Super-microbes engineered to solve world environmental problems

Environmental problems, such as depleting natural resources, highlight the need to establish a renewable chemical industry. Metabolic engineering enhances the production of chemicals made by microbes in so-called "cell factories". ...

'Promiscuous' enzymes still prevalent in metabolism

Open an undergraduate biochemistry textbook and you will learn that enzymes are highly efficient and specific in catalyzing chemical reactions in living organisms, and that they evolved to this state from their "sloppy" and ...

To starve a tumor

(PhysOrg.com) -- Since the 1920s, scientists have known that cancer cells generate energy differently than normal cells, a phenomenon dubbed the 'Warburg effect' after its discoverer, German biochemist Otto Warburg. However, ...

Building a complete metabolic model

Investigators at Burnham Institute for Medical Research, University of California, San Diego, The Scripps Research Institute, Genomics Institute of the Novartis Research Foundation and other institutions have constructed ...

NMR on a microscale

(PhysOrg.com) -- The technique well known from its use in MRI scanning - actually based on nuclear magnetic resonance (NMR) - can now also be applied to extremely small samples thanks to an ingenious combination of a compact ...

Chip simulates metabolism of medicine in human body

(PhysOrg.com) -- A tiny electrochemical cell, developed by researchers of the MESA+ Institute for Nanotechnology, The Netherlands, is able to mimick the behaviour of medicine inside a human body. This chip is presented in ...

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