Democratizing high-throughput single molecule force analysis

From the tension of contracting muscle fibers to hydrodynamic stresses within flowing blood, molecules within our bodies are subject to a wide variety of mechanical forces that directly influence their form and function. ...

Preventing protein unfolding

When the body loses its ability to fold proteins into the correct shapes, the result can be irreversible and tragic. The accumulation of unfolded or misfolded proteins in the brain causes many devastating neurodegenerative ...

Major advance made in imaging of a single-molecule switch

Development of future technologies will be greatly aided by understanding and extracting molecular-level characteristics. A University of Tsukuba research group has established a three-dimensional probe that can depict the ...

Researchers create perovskites via mechanochemistry

Perovskites, substances that perfectly absorb light, are the future of solar energy. Now, a rapid and environmentally safe method of production has been developed by chemists from Warsaw, Poland. Perovskites can now be synthesized ...

New force sensing method reveals how cells sense tissue stiffness

Just as we can feel whether we are lying on a soft blanket or hard rocks, our cells sense whether they are in a soft or rigid mechanical environment. However, the molecular mechanisms underlying cells' ability to detect tissue ...

Mechanical forces control the architecture of bacterial biofilms

As hide-outs for bacteria, biofilms cause problems for antibiotic treatment or the cleaning of medical tubes. They contribute to the spreading of antibiotic-resistant bacterial strains. A biofilm is created when bacteria ...

Just a touch of skyrmions

Ancient memory devices such as handwriting were based on mechanical energy—but in the modern world they have given way to devices based generally on electrical manipulation.

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