To age or not to age? How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes—critically important cellular structures—are crucial ...
Cell & Microbiology
Nov 21, 2023
0
2
In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed.
Cell & Microbiology
Oct 6, 2022
0
102
Today in Nature, University of Pittsburgh researchers describe for the first time a pathway by which cells repair damaged lysosomes, structures that contribute to longevity by recycling cellular trash. The findings are an ...
Cell & Microbiology
Sep 7, 2022
0
18
Like thieves that constantly look for ways to evade capture, Salmonella enterica, a disease-causing bacterium, uses various tactics to escape the human body's defense mechanisms. In a new study, researchers from the Department ...
Cell & Microbiology
May 26, 2023
0
49
Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme -preventing or reducing organ and central nervous system damage ...
Cell & Microbiology
Nov 9, 2009
0
0
Small but mighty, lysosomes play a surprisingly important role in cells despite their diminutive size. Making up only 1-3% of the cell by volume, these small sacs are the cell's recycling centers, home to enzymes that break ...
Cell & Microbiology
Sep 21, 2022
0
121
(PhysOrg.com) -- A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has for the first time determined the mechanism of one of the cell’s 'recycling' enzymes, human alpha-galactosidase ...
Biochemistry
Feb 2, 2010
0
0
Lysosomes are cellular waste disposal organelles containing potent enzymes. These enzymes can cause cellular damage if they leak out of ruptured lysosomes. In a recent study led by Osaka University, researchers found that ...
Cell & Microbiology
Sep 28, 2020
0
38
A team of researchers at the Center for Self-assembly and Complexity, within the Institute for Basic Science (IBS) have observed a normal physiological process, called "self-eating", that cells use to recycle their components. ...
Biochemistry
Feb 19, 2018
0
32
(Phys.org)—The seeds of greenhouse-grown corn could hold the key to treating a rare, life-threatening childhood genetic disease, according to researchers from Simon Fraser University.
Biochemistry
Sep 21, 2012
0
0
