Related topics: cancer · cancer cells · chemotherapy · patients · smokers

Engineers model mutations causing drug resistance

Whether it is a drug-resistant strain of bacteria, or cancer cells that no longer react to the drugs intended to kill them, diverse mutations make cells resistant to chemicals, and "second generation" approaches are needed. ...

Micro-pollution ravaging China and South Asia: study

Nearly 90 percent of the 200 cities beset by the world's highest levels of deadly micro-pollution are in China and India, with most of the rest in Pakistan and Indonesia, researchers reported Tuesday.

Air pollution costs $2.9 trillion a year: NGO

The global cost of air pollution caused by fossil fuels is $8 billion a day, or roughly 3.3 percent of the entire world's economic output, an environmental research group said on Wednesday.

US official: Research finds uranium in Navajo women, babies

About a quarter of Navajo women and some infants who were part of a federally funded study on uranium exposure had high levels of the radioactive metal in their systems, decades after mining for Cold War weaponry ended on ...

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Lung cancer

Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. The vast majority of primary lung cancers are carcinomas of the lung, derived from epithelial cells. Lung cancer, the most common cause of cancer-related death in men and the second most common in women (after breast cancer), is responsible for 1.3 million deaths worldwide annually. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.

The main types of lung cancer are small cell lung carcinoma and non-small cell lung carcinoma. This distinction is important, because the treatment varies; non-small cell lung carcinoma (NSCLC) is sometimes treated with surgery, while small cell lung carcinoma (SCLC) usually responds better to chemotherapy and radiation. The most common cause of lung cancer is long-term exposure to tobacco smoke. The occurrence of lung cancer in nonsmokers, who account for as many as 15% of cases , is often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution, including secondhand smoke.

Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed via bronchoscopy or CT-guided biopsy. Treatment and prognosis depend upon the histological type of cancer, the stage (degree of spread), and the patient's performance status. Possible treatments include surgery, chemotherapy, and radiotherapy. With treatment, the five-year survival rate is 14%.

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