A molecule that destroys normal metabolism is found

Overeating in mice triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes. The new study, ...

Mice with fewer insulin-signaling receptors don't live longer

Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even ...

Protective hinge process enables insulin to bind to cells

Since its landmark discovery in 1922, insulin has improved the health and extended the lives of more than 500 million people worldwide with diabetes mellitus. Yet the question of how this key hormone binds to its target cells ...

Revealing the biology of insulin production

The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis.

Discovery may lead to safer drinking water, cheaper medicine

A discovery that may pave the way to helping reduce health hazards such as E. coli in water could also make chemicals and drugs such as insulin cheaper to produce and their production more environmentally friendly.

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