Exploring the limits of G protein-coupled receptors

How do signals from outside the cell cause a response inside it? Such outside signals could be hormones or neurotransmitters. To notice them, the cell's surface possesses receptors. One of the key classes of such receptors ...

How plants' threat-detection mechanisms raise the alarm

New work led by Carnegie's Zhiyong Wang untangles a complex cellular signaling process that underpins plants' ability to balance expending energy on growth and defending themselves from pathogens. These findings, published ...

How cells navigate in messy environments

Your cells need to get around. For example, immune cells must roam around your body to locate sites of infection, and neurons must migrate to specific positions in the brain during development. But cells do not have eyes ...

Function follows form in plant immunity

Scientists from the Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne, Germany, have discovered a novel biochemical mechanism explaining how immune proteins defend plants against invading ...

New tool reveals how immune cells find their targets

The human body has millions of unique B and T cells that roam the body, looking for microbial invaders. These immune cells' ability to recognize harmful microbes is critical to successfully fighting off infection.

New computational method opens window into immune cell behavior

Immune cells have many jobs to do: Some identify infected cells and eliminate them. Others help rein in inflammation to prevent damage to healthy tissue. And many are critical components of cancer treatment. Researchers know ...

How density governs receptor activation on immune cells

Scientists from within the Antibody and Vaccine Group at the University of Southampton have gained novel insights into how an important class of immune receptors called tumor necrosis factor receptors (TNFR) are activated.

page 2 from 9