How can human cells pack 3-meter-long DNA into their tiny nuclei and unpack it only where and when it is needed? This fascinating process is far from being completely understood.
Biotechnology
Feb 5, 2020
0
8
The genetic material of our cells—DNA—exists in a high-order structure called chromatin. Chromatin consists of DNA wrapped around histone proteins and efficiently packs DNA into a small volume. Moreover, using a spool ...
Molecular & Computational biology
Jan 23, 2020
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19
Researchers have used mass spectroscopy to determine the absolute copy numbers of nuclear proteins and histone modifications in the Drosophila embryo. The results provide new insights into the mechanisms of animal development.
Plants & Animals
Oct 22, 2019
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4
By using proteins that naturally bind and arrange DNA inside cells, a KAUST-led team has devised a plug-and-play strategy for building stable, custom-designed nanostructures.
Nanomaterials
Oct 14, 2019
0
29
As an organism grows and responds to its environment, genes in its cells are constantly turning on and off, with different patterns of gene expression in different cells. But can changes in gene expression be passed on from ...
Biotechnology
Mar 20, 2019
1
61
Since the time of ancient Egypt, humans have been making and breaking secret codes to retain and gain critical information. Human life itself is based upon a genetic code of DNA or RNA sequences which cells read and translate ...
Biochemistry
Nov 8, 2018
0
16
A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU), in collaboration with scientists from Tsinghua University in China, the Rockefeller University, and the University ...
Biochemistry
Nov 7, 2018
0
68
Trypanosoma brucei, which causes sleeping sickness, evades the immune system by repeatedly altering the structure of its surface coat. Sequencing of its genome and studies of its 3-D genome architecture have now revealed ...
Cell & Microbiology
Oct 18, 2018
0
36
Researchers at the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical compounds that inhibit an enzyme ...
Biochemistry
Sep 6, 2018
0
47
With a new groundbreaking technique, researchers from University of Copenhagen have managed to identify a protein that is responsible for cellular memory transmission when cells divide. The finding is crucial for understanding ...
Cell & Microbiology
Aug 16, 2018
1
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