A next-generation gene-editing system developed by Carnegie Mellon University and Yale University scientists has successfully cured a genetic blood disorder in living mice using a simple IV treatment. Unlike the popular CRISPR ...
Biotechnology
Oct 26, 2016
0
1648
With over 75 million baby boomers in the U.S. alone, age-related diseases are a major concern in the health care system. The connection between aging and cancer has become a pillar in medicine: we know that as we age, our ...
Biotechnology
Oct 7, 2016
0
20
Researchers led by Carnegie Mellon University Professor of Biological Sciences Chien Ho have developed a new method for preparing mesenchymal stem cells (MSCs) that not only leads to the production of more native stem cells, ...
Cell & Microbiology
May 18, 2016
0
248
Simple physics may play a larger role than previously thought in helping control key bodily processes such as how the body fights infection.
General Physics
Feb 8, 2016
2
32
A study from Patrick Matthias and his group at the FMI challenges a widely accepted model on how epigenome dynamics control the differentiation of hematopoietic cells. The plasticity of pluripotent stem cells was thought ...
Cell & Microbiology
Oct 20, 2015
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50
Researchers at the Stanford University School of Medicine have discovered the stem cell in mice that gives rise to bone, cartilage and a key part of bone marrow called the stroma.
Cell & Microbiology
Jan 15, 2015
0
36
Hematopoietic stem cells (HSCs) give rise to all blood and immune cells throughout the life of vertebrate organisms, from zebrafish to humans. But details of their genesis remain elusive, hindering efforts to develop induced ...
Cell & Microbiology
Nov 6, 2014
0
0
When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete ...
Cell & Microbiology
May 21, 2013
0
0
Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...
Cell & Microbiology
Oct 5, 2012
0
0
Not all adult stem cells are created equal. Some are busy regenerating worn out or damaged tissues, while their quieter brethren serve as a strategic back-up crew that only steps in when demand shoots up. Now, researchers ...
Cell & Microbiology
Jul 19, 2012
0
0
