A helicase, Pfh1, can thanks to several different mechanisms protect the genome from DNA obstacles and damages associated with cancer. This is shown in a new doctoral thesis at Umeå University, Sweden.
Molecular & Computational biology
Feb 11, 2019
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Roughly six feet of DNA are packed into every human cell, so it is not surprising that our genetic material occasionally folds into odd shapes such as hairpins, crosses and clover leafs. But these structures can block the ...
Cell & Microbiology
Jun 3, 2013
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Two scientists at the Johns Hopkins University School of Medicine have unraveled aspects of how DNA organizes and preserves genetic information. Newly published research by Cynthia Wolberger, Ph.D., and James Berger, Ph.D., ...
Molecular & Computational biology
May 22, 2019
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Loading of replicative helicases onto DNA is a key event during the initiation of chromosomal DNA replication. It takes place at specific chromosomal regions termed origins and is facilitated by the ORC protein complex. By ...
Molecular & Computational biology
Sep 21, 2020
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