Balance is key to many physiological functions and it is especially true in the production and regulation of proteins. A balance of proteins in cells helps maintain health, but an unhealthy clumping can lead to a variety ...
Cell & Microbiology
Nov 6, 2017
1
145
Researchers at RIKEN have uncovered a mechanism by which the effects of stress in the fly species Drosophila are inherited epigenetically over many generations through changes to the structure of chromatin, the material that ...
Cell & Microbiology
Jun 23, 2011
1
0
(Phys.org) —University of Delaware researchers have identified a protein, hiding in plain sight, that acts like a bodyguard to help protect and stabilize another key protein, that when unstable, is involved in Crohn's disease. ...
Biochemistry
Jul 17, 2014
0
0
For decades, molecular biologists studying a class of molecular chaperones known as heat shock proteins (Hsp70s) have relied on the Hsp70s found in bacteria as the model system. Now one of the world's experts on the molecule ...
Biochemistry
Nov 9, 2018
0
54
Whitehead Institute researchers have determined how the master transcriptional regulator of the heat shock response, known as heat shock factor 1 (HSF1), is activated and controlled. This insight could lead to treatments ...
Cell & Microbiology
Nov 14, 2016
0
5
In one fell swoop, Cornell researchers have discovered mechanisms that control the function of a fat and obesity gene while at the same time answering a long-standing question about how cells respond to stress.
Cell & Microbiology
Oct 29, 2015
0
856
Protein aggregates that form after a cell is exposed to high, non-lethal temperatures appear to be part of an organized response to stress, and not the accumulation of damaged proteins en route to destruction. Reporting in ...
Cell & Microbiology
Sep 10, 2015
0
16
Lake Baikal, with its exceptional species diversity and unique wildlife, is a UNESCO Natural World Heritage Site. As part of the Helmholtz Russia Research Group LaBeglo, UFZ researchers are studying the impact of climate ...
Environment
Jul 26, 2017
0
8
Many enzymes work only with a co-trainer, of sorts. Scientists at the Technische Universitaet Muenchen and the Cluster of Excellence Nanosystems Initiative Munich show what this kind of cooperation looks like in detail using ...
Cell & Microbiology
Jun 30, 2014
0
0
Researchers from the Verstreken lab (VIB-KU Leuven) have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body. In addition to its well-known role as a protein chaperone, ...
Cell & Microbiology
Sep 7, 2018
0
2
