New insight into the regulation of stem cells and cancer cells

Scientists at the Gladstone Institutes have gained new insight into the delicate relationship between two proteins that, when out of balance, can prevent the normal development of stem cells in the heart and may also be important ...

True love: How transcription factors interact to create a heart

Scientists at the Gladstone Institutes have discovered that three transcription factors—proteins that direct gene expression—interact with each other and the genome to influence how a heart forms in an embryo. Without ...

New tool to accelerate drug discovery

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones—or chemical messengers—bind to cell membrane receptors to fine tune how the cell behaves. Once ...

Understanding congenital heart defects, one chicken at a time

Approximately 10 percent of infants are born with a congenital heart defect, with one of the most common being persistent truncus arteriosus—a hole in the heart. In a healthy baby, deoxygenated blood is pumped through a ...

Molecular researchers discover novel gene linked to aging hearts

Researchers at the University of Ottawa Heart Institute (UOHI) have identified a novel gene in the nucleus of muscle and brain cells that affects heart development and the aging process. Their investigation brings the promise ...

Sanford-Burnham research projects selected to go to space

Sanford-Burnham Medical Research Institute (Sanford-Burnham) today announced that two of the Institute's research teams have won Space Florida's International Space Station (ISS) Research Competition. Eight teams were selected ...

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